SRRT anticorps (N-Term)

N° du produit ABIN5538733

Détail du produit anti-SRRT anticorps

Antigène: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Épitope: AA 54-81, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRRT est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SRRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human SRRT.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SRRT

Antigène: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Autre désignation: SRRT (SRRT Produits)

Synonymes: anticorps CG7843, anticorps Dmel\\CG7843, anticorps anon-WO0118547.166, anticorps ars2, anticorps ars2-A, anticorps serrate, anticorps ARS2, anticorps ASR2, anticorps 2810019G02Rik, anticorps ASR2A, anticorps ASR2B, anticorps ASR2C, anticorps ASR2D, anticorps Ars2, anticorps Asr2, anticorps MGC92060, anticorps CHUNP6881, anticorps zgc:92060, anticorps Arsenic resistance protein 2, anticorps serrate, RNA effector molecule S homeolog, anticorps serrate, RNA effector molecule, anticorps serrate RNA effector molecule homolog (Arabidopsis), anticorps Ars2, anticorps srrt.S, anticorps SRRT, anticorps Srrt, anticorps srrt

Sujet: SRRT acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.

Poids moléculaire: 101 kDa

ID gène: 51593

UniProt: Q9BXP5

Pathways: Signalisation Notch, Stem Cell Maintenance