DEAF1 anticorps (C-Term)

N° du produit ABIN5539344

Détail du produit anti-DEAF1 anticorps

Antigène: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Épitope: AA 474-502, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEAF1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DEAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human DEAF1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DEAF1

Antigène: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Autre désignation: DEAF1 (DEAF1 Produits)

Synonymes: anticorps AU042387, anticorps C230009B13Rik, anticorps NUDR, anticorps SPN, anticorps ZMYND5, anticorps MYND5, anticorps spn, anticorps DEAF1, anticorps nudr, anticorps zmynd5, anticorps CG8567, anticorps DEAF-1, anticorps Deaf-1, anticorps Dmel\\CG8567, anticorps deaf1, anticorps l(3)76BDv, anticorps deformed epidermal autoregulatory factor 1 (Drosophila), anticorps DEAF1, transcription factor, anticorps DEAF1 transcription factor, anticorps deformed epidermal autoregulatory factor 1 homolog, anticorps Deformed epidermal autoregulatory factor-1, anticorps Deaf1, anticorps DEAF1, anticorps LOC509260, anticorps deaf1, anticorps deaf-1

Sujet: Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm.

Poids moléculaire: 59 kDa

ID gène: 10522

UniProt: O75398

Pathways: Tube Formation