RanBP3 anticorps (AA 235-445)

N° du produit ABIN5540645

Détail du produit anti-RanBP3 anticorps

Antigène: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Épitope: AA 235-445

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RanBP3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: Recognizes Human RANBP3. Other species not tested.

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human RANBP3 (235-445aa) purified from E. coli.

Clone: AT12E11

Isotype: IgG1

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur RanBP3

Antigène: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Autre désignation: ranbp3 (RANBP3 Produits)

Synonymes: anticorps 2610024N24Rik, anticorps AA408221, anticorps ranbp3, anticorps MGC79798, anticorps zgc:63485, anticorps RAN binding protein 3, anticorps RAN binding protein 3 L homeolog, anticorps RAN binding protein 3a, anticorps RANBP3, anticorps Ranbp3, anticorps ranbp3.L, anticorps ranbp3, anticorps ranbp3a

Sujet: The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.

UniProt: Q9H6Z4