PIK3 gamma anticorps (AA 1-100)

N° du produit ABIN5542535

Cet anticorps Souris Monoclonal détecte spécifiquement PIK3 gamma dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour PIK3 gamma anticorps (AA 1-100) (ABIN5542535)

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PIK3 gamma est non-conjugé

Application: ELISA

Clone: 4B5D2

Détail du produit anti-PIK3 gamma anticorps

Épitope: AA 1-100

Fonction: PIK3CG Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PIK3 gamma

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Autre désignation: PIK3CG

Sujet: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 126.5 kDa

ID gène: 5294

UniProt: P48736

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling