CD41, CD61 anticorps
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- Antigène Voir toutes CD41, CD61 Anticorps
- CD41, CD61 (CD41,CD61)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD41, CD61 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Specificité
- The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Human platelets
- Clone
- PAC-1
- Isotype
- IgM kappa
- Top Product
- Discover our top product CD41, CD61 Anticorps primaire
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anti-CD41,CD61 antibody
Reactivité: Humain, Boeuf (Vache) FACS, IP, ELISA, ICC Hôte: Souris Monoclonal IVA30 unconjugated
anti-CD41,CD61 antibody (PE)Reactivité: Humain FACS Hôte: Souris Monoclonal PAC-1 PE
anti-CD41,CD61 antibody (PerCP)Reactivité: Humain FACS Hôte: Souris Monoclonal PAC-1 PerCP
anti-CD41,CD61 antibody (FITC)Reactivité: Humain FACS Hôte: Souris Monoclonal PAC-1 FITC
anti-CD41,CD61 antibodyReactivité: Humain FACS, IF, DNA Mic Hôte: Souris Monoclonal A2A9-6 unconjugated
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- Indications d'application
- Flow cytometry: Recommended dilution: 2-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- CD41, CD61 (CD41,CD61)
- Autre désignation
- CD41/CD61 (CD41, CD61 Produits)
- Sujet
- CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa
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