HFE anticorps

N° du produit ABIN5647142

Détail du produit anti-HFE anticorps

Antigène: HFE (Hemochromatosis (HFE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HFE est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity purified

Immunogène: Amino acids Q82-R199 from the human protein were used as the immunogen for the HFE antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HFE antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the HFE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HFE

Antigène: HFE (Hemochromatosis (HFE))

Autre désignation: HFE (Hereditary hemochromatosis protein) (HFE Produits)

Synonymes: anticorps HFE1, anticorps HH, anticorps HLA-H, anticorps MVCD7, anticorps TFQTL2, anticorps MR2, anticorps hemochromatosis, anticorps HFE, anticorps Hfe

Sujet: Human hemochromatosis protein, also known as HFE, is a protein which in humans is encoded by the HFE gene. The gene is located on short arm of chromosome 6 at location 6p21.3. It is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.

UniProt: Q30201

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process