MXD1 anticorps

N° du produit ABIN5647191

Détail du produit anti-MXD1 anticorps

Antigène: MXD1 (MAX Dimerization Protein 1 (MXD1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MXD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids M1-L221 was used as the immunogen for the MAD antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MAD antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the MAD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur MXD1

Antigène: MXD1 (MAX Dimerization Protein 1 (MXD1))

Autre désignation: MAD / MXD1 / Max dimerization protein 1 (MXD1 Produits)

Synonymes: anticorps MXD1, anticorps si:dkey-202n14.4, anticorps xmad1, anticorps BHLHC58, anticorps MAD, anticorps MAD1, anticorps AW122478, anticorps Mad, anticorps Mad1, anticorps Mad-1, anticorps MAX dimerization protein 1, anticorps MAX dimerization protein 1 L homeolog, anticorps max dimerization protein 1, anticorps MXD1, anticorps mxd1, anticorps mxd1.L, anticorps Mxd1

Sujet: MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: Q05195