STT3A anticorps (AA 476-507)

N° du produit ABIN5647816

Détail du produit anti-STT3A anticorps

Antigène: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Épitope: AA 476-507

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STT3A est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée (Details): Expected species reactivity: Mouse,Bovine

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 476-507 from the human protein was used as the immunogen for the STT3A antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western blot: 1:1000-2000

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the STT3A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur STT3A

Antigène: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Autre désignation: STT3A (STT3A Produits)

Synonymes: anticorps cb437, anticorps wu:fb38c11, anticorps AA408947, anticorps BB081708, anticorps Itm1, anticorps ITM1, anticorps STT3-A, anticorps TMC, anticorps STT3A, subunit of the oligosaccharyltransferase complex (catalytic), anticorps STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae), anticorps STT3A, catalytic subunit of the oligosaccharyltransferase complex, anticorps stt3a, anticorps Stt3a, anticorps STT3A

Sujet: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A is the catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

ID gène: 3703

UniProt: P46977