Calpastatin anticorps (C-Term)

N° du produit ABIN5663576

Détail du produit anti-Calpastatin anticorps

Antigène: Calpastatin (CAST)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpastatin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TIPPEYRHLL DDNGQDKPVK PPTKKSEDSK KPADDQDPID ALSGDLDSCP STTETSQNTA KDKCKKAASS SKAPKNGGKA KDSAKTTEET SKPKDD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human CAST (NP_001177371.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Calpastatin

Antigène: Calpastatin (CAST)

Autre désignation: CAST (CAST Produits)

Synonymes: anticorps BS-17, anticorps calp3, anticorps CAST, anticorps sb:cb966, anticorps zgc:194249, anticorps cast, anticorps DKFZp469E0716, anticorps calpastatin, anticorps calpastatin S homeolog, anticorps Calpastatin, anticorps CAST, anticorps Cast, anticorps cast.S, anticorps cast, anticorps VDBG_09182, anticorps ical

Sujet: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.,CAST,BS-17,PLACK,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neuron marker,Synapse marker,CAST

Poids moléculaire: 63 kDa/71- 84 kDa

ID gène: 831

UniProt: P20810