Vimentin anticorps
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- Antigène Voir toutes Vimentin (VIM) Anticorps
- Vimentin (VIM)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Vimentin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogène
- Fusion protein of human VIM
- Isotype
- IgG
- Top Product
- Discover our top product VIM Anticorps primaire
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- Indications d'application
- Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:100, IF: 1:20-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C/-80 °C
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Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." dans: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).
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Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." dans: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).
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- Antigène
- Vimentin (VIM)
- Autre désignation
- VIM (VIM Produits)
- Synonymes
- anticorps CTRCT30, anticorps cb28, anticorps vime, anticorps vim, anticorps vim1, anticorps vim2, anticorps VIM, anticorps Vimentin, anticorps vim4, anticorps vimentin, anticorps vimentin L homeolog, anticorps vimentin S homeolog, anticorps VIM, anticorps Vim, anticorps vim, anticorps vim.L, anticorps vim.S
- Sujet
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The cytoskeleton consists of three types of cytosolic fibers: microfilaments (actin filaments), intermediate filaments, and microtubules. Major types of intermediate filaments are distinguished by their cell specific expression: cytokeratins (epithelial cells), glial fibrillary acidic protein (GFAP) (glial cells), desmin (skeletal, visceral, and certain vascular smooth muscle cells), vimentin (mesenchyme origin), and neurofilaments (neurons). GFAP and vimentin form intermediate filaments in astroglial cells and modulate their motility and shape. In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. Thus, GFAP is commonly used as a marker for intracranial and intraspinal tumors arising from astrocytes. Vimentin is present in sarcomas, but not carcinomas, and its expression is examined in conjunction with that of other markers to distinguish between the two. Vimentins dynamic structural changes and spatial re-organization in response to extracellular stimuli help to coordinate various signaling pathways. Phosphorylation of vimentin at Ser56 in smooth muscle cells regulates the structural arrangement of vimentin filaments in response to serotonin. Remodeling of vimentin and other intermediate filaments is important during lymphocyte adhesion and migration through the endothelium.
Synonyms: VIM, FLJ36605 , Vimentin - ID gène
- 7431
- UniProt
- P08670
- Pathways
- Caspase Cascade in Apoptosis
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