PLAUR anticorps (AA 23-305)

N° du produit ABIN5663892

Détail du produit anti-PLAUR anticorps

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Épitope: AA 23-305

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAUR est non-conjugé

Application: Western Blotting (WB)

Séquence: LRCMQCKTNG DCRVEECALG QDLCRTTIVR LWEEGEELEL VEKSCTHSEK TNRTLSYRTG LKITSLTEVV CGLDLCNQGN SGRAVTYSRS RYLECISCGS SDMSCERGRH QSLQCRSPEE QCLDVVTHWI QEGEEGRPKD DRHLRGCGYL PGCPGSNGFH NNDTFHFLKC CNTTKCNEGP ILELENLPQN GRQCYSCKGN STHGCSSEET FLIDCRGPMN QCLVATGTHE PKNQSYMVRG CATASMCQHA HLGDAFSMNH IDVSCCTKSG CNHPDLDVQY RSG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 23-305 of human PLAUR (NP_002650.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLAUR

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Autre désignation: PLAUR (PLAUR Produits)

Synonymes: anticorps Cd87, anticorps u-PAR, anticorps uPAR, anticorps CD87, anticorps U-PAR, anticorps UPAR, anticorps URKR, anticorps Par, anticorps Plaur3, anticorps uPAR-2, anticorps uPAR-3, anticorps PLAUR, anticorps plasminogen activator, urokinase receptor, anticorps Plaur, anticorps PLAUR

Sujet: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.,PLAUR,CD87,U-PAR,UPAR,URKR,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Extracellular Matrix,Immunology & Inflammation,CD markers,Cardiovascular,Blood,PLAUR

Poids moléculaire: 31 kDa/32 kDa/36 kDa

ID gène: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process