Lamin B1 anticorps
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- Antigène Voir toutes Lamin B1 (LMNB1) Anticorps
- Lamin B1 (LMNB1)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Lamin B1 est non-conjugé
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Application
- Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Fusion protein of human LMNB1
- Isotype
- IgG
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- Indications d'application
- Recommended dilutions: WB: 1:500-1:1000, IHC: 1:50-1:100, IF: 1:20-1:50, IP: 1:20-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C/-80 °C
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- Antigène
- Lamin B1 (LMNB1)
- Autre désignation
- LMNB1 (LMNB1 Produits)
- Synonymes
- anticorps MGC52550, anticorps Lamin-L(I), anticorps lamin-b, anticorps lmn, anticorps lmn2, anticorps lmnb, anticorps LMNB1, anticorps ADLD, anticorps LMN, anticorps LMN2, anticorps LMNB, anticorps fc06g01, anticorps wu:fc06g01, anticorps lamin B1 L homeolog, anticorps lamin B1, anticorps lmnb1.L, anticorps lmnb1, anticorps LMNB1, anticorps Lmnb1
- Sujet
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Lamins are nuclear membrane structural components that are important in maintaining normal cell functions, such as cell cycle control, DNA replication, and chromatin organization. Lamins have been subdivided into types A and B. Type-A lamins consist of lamin A and C, arising from alternative splicing. Lamin A and C are cleaved by caspases into large (41-50 kDa) and small (28 kDa) fragments, which can be used as markers for apoptosis. Type-B lamins consist of lamin B1 and B2, encoded by separate genes. Lamin B1 is also cleaved by caspases during apoptosis. Research studies have shown that duplication of the lamin B1 gene is correlated with the pathogenesis of the neurological disorder adult-onset leukodystrophy.
Synonyms: ADLD, LMN, LMN2, LMNB, MGC111419, Lamin B1 - ID gène
- 4001
- UniProt
- P20700
- Pathways
- Apoptose, Caspase Cascade in Apoptosis