Recombinant CD40L (Ruplizumab Biosimilar) anticorps

N° du produit ABIN5668046

Détail du produit anti-CD40L (Ruplizumab Biosimilar) anticorps

Antigène: CD40L (Ruplizumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40L (Ruplizumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Blocking Reagent (BR)

Specificité: The antibody binds to CD40L with an IC50 of 0.845 μg/mL.

Attributs du produit:

OriginalSpeciesName: Human

OriginalFormat: IgG1

Purification: Purified antibody.

Pureté: > 98 % as determined by SDS-PAGE

niveau d'endotoxine: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogène: Human CD40L

Clone: Hu5c8

Isotype: IgG1 kappa

Information d'application

Indications d'application: The antibody binds specifically to CD40L, a surface receptor expressed on activated T cells which acts as a costimulatory molecule to trigger immune responses. The antibody neutralises CD40L function, as it blocks the interaction between CD40 and CD40L. When injected into cynomolgus monkeys, the original therapeutic antibody was found to have a T1/2 of 531? ±?155 hours.

Commentaires:

NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD40L (Ruplizumab Biosimilar)

Antigène: CD40L (Ruplizumab Biosimilar)

Abstract: CD40L (Ruplizumab Biosimilar) Produits

Synonymes: anticorps CD154, anticorps CD40L, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TNFSF5, anticorps TRAP, anticorps gp39, anticorps hCD40L, anticorps CD40 ligand, anticorps CD40LG

Classe de substances: Biosimilar

Sujet: CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP

UniProt: P29965