CRHR1 anticorps (Internal Region)

N° du produit ABIN6261033

Détail du produit anti-CRHR1 anticorps

Antigène: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRHR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CRHR1 Antibody detects endogenous levels of total CRHR1.

Homologie: Pig,Zebrafish,Bovine

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CRHR1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CRHR1

Antigène: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Autre désignation: CRHR1 (CRHR1 Produits)

Synonymes: anticorps CRF-R, anticorps CRF-R-1, anticorps CRF-R1, anticorps CRF1, anticorps CRFR-1, anticorps CRFR1, anticorps CRH-R-1, anticorps CRH-R1, anticorps CRH-R1h, anticorps CRHR, anticorps CRHR1L, anticorps CRHR1f, anticorps Crhr, anticorps crhr1, anticorps crhr1-A, anticorps CRHR1, anticorps CRHR1-IT1-CRHR1, anticorps MGC57346-CRHR1, anticorps corticotropin releasing hormone receptor 1, anticorps corticotropin releasing hormone receptor 1, gene 2 S homeolog, anticorps corticotropin-releasing factor receptor 1, anticorps LINC02210-CRHR1 readthrough, anticorps CRHR1, anticorps Crhr1, anticorps crhr1.2.S, anticorps LOC610380, anticorps LOC100065598, anticorps LINC02210-CRHR1, anticorps crhr1

Sujet:

Description: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.

Gene: CRHR1

Poids moléculaire: 51 kDa

ID gène: 104909134, 1394

UniProt: P34998

Pathways: Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity