PTPRM anticorps (AA 565-742)

N° du produit ABIN5684049

Détail du produit anti-PTPRM anticorps

Antigène: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Épitope: AA 565-742

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTPRM est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human PTPRM (AA: extra 565-742) expressed in E. coli.

Clone: 8F1C10

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur PTPRM

Antigène: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Autre désignation: PTPRM (PTPRM Produits)

Synonymes: anticorps cb984, anticorps ptprm, anticorps zgc:110218, anticorps PTPRM, anticorps p-ptp-mu, anticorps ptprl1, anticorps r-ptpu, anticorps rptpm, anticorps rptpu, anticorps PTPRL1, anticorps R-PTP-MU, anticorps RPTPM, anticorps RPTPU, anticorps hR-PTPu, anticorps RPTPmu, anticorps mKIAA4044, anticorps protein tyrosine phosphatase, receptor type, M, a, anticorps protein tyrosine phosphatase, receptor type M, anticorps protein tyrosine phosphatase, receptor type, M, b, anticorps receptor-type tyrosine-protein phosphatase mu, anticorps protein tyrosine phosphatase, receptor type, M, anticorps ptprma, anticorps PTPRM, anticorps ptprmb, anticorps ptprm, anticorps LOC100550127, anticorps LOC100564083, anticorps Ptprm

Sujet:

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Aliases: RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU

Poids moléculaire: 163.7 kDa

ID gène: 5797

HGNC: 2215