PTPRM anticorps

N° du produit ABIN7238327

Détail du produit anti-PTPRM anticorps

Antigène: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRM est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human PTPRM

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTPRM

Antigène: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Autre désignation: PTPRM (PTPRM Produits)

Synonymes: anticorps cb984, anticorps ptprm, anticorps zgc:110218, anticorps PTPRM, anticorps p-ptp-mu, anticorps ptprl1, anticorps r-ptpu, anticorps rptpm, anticorps rptpu, anticorps PTPRL1, anticorps R-PTP-MU, anticorps RPTPM, anticorps RPTPU, anticorps hR-PTPu, anticorps RPTPmu, anticorps mKIAA4044, anticorps protein tyrosine phosphatase, receptor type, M, a, anticorps protein tyrosine phosphatase, receptor type M, anticorps protein tyrosine phosphatase, receptor type, M, b, anticorps receptor-type tyrosine-protein phosphatase mu, anticorps protein tyrosine phosphatase, receptor type, M, anticorps ptprma, anticorps PTPRM, anticorps ptprmb, anticorps ptprm, anticorps LOC100550127, anticorps LOC100564083, anticorps Ptprm

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

NCBI Accession: NP_002836

UniProt: P28827