TNFRSF11A anticorps (AA 30-212)
Aperçu rapide pour TNFRSF11A anticorps (AA 30-212) (ABIN5684101)
Antigène
Voir toutes TNFRSF11A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 30-212
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Fonction
- TNFRSF11A Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human TNFRSF11A (AA: 30-212) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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Autre désignation
- TNFRSF11A
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Sujet
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
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Poids moléculaire
- 66 kDa
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ID gène
- 8792
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UniProt
- Q9Y6Q6
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Pathways
- Signalisation NF-kappaB
Antigène
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