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Vinculin anticorps (N-Term)
VCL
Reactivité: Humain, Souris, Rat, Lapin, Poulet
WB, ELISA
Hôte: Souris
Monoclonal
8B5
unconjugated
N° du produit ABIN5688766
Détail du produit anti-Vinculin anticorps
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Antigène
Voir toutes Vinculin (VCL) Anticorps
Vinculin (VCL)
Épitope
Tous les épitopes à travers Vinculin Anticorps.
N-Term
Reactivité
Toutes les réactivités sur Vinculin Anticorps
Humain, Souris, Rat, Lapin, Poulet
Hôte
Toutes les hôtes sur Vinculin Anticorps
Souris
Clonalité
Toutes les clonalités sur Vinculin Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Vinculin Anticorps
Cet anticorp Vinculin est non-conjugé
Application
Tous les applications à travers Vinculin Anticorps.
Western Blotting (WB), ELISA
Specificité
Vinculin antibody is human, mouse, rat, rabbit and chicken reactive. At least three isoforms of Vinculin are known to exist.
Purification
Vinculin antibody is purified via Protein A prification.
Immunogène
Vinculin antibody was raised against a 23 amino acid peptide near the amino terminus of human Vinculin.
Clone
8B5
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
Vinculin antibody can be used for detection of Vinculin by Western blot at 0.5 - 1 μ,g/mL.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Vinculin Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Vinculin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Détails sur Vinculin
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Antigène
Vinculin (VCL)
Autre désignation
Vinculin (VCL Produits )
Synonymes
anticorps CMD1W, anticorps CMH15, anticorps MV, anticorps MVCL, anticorps VCL, anticorps im:6902790, anticorps hm:zehn2160, anticorps DDBDRAFT_0186762, anticorps DDBDRAFT_0232320, anticorps DDB_0186762, anticorps DDB_0232320, anticorps 9430097D22, anticorps AA571387, anticorps AI462105, anticorps AW545629, anticorps CG3299, anticorps CT11081, anticorps Dmel\\CG3299, anticorps Dmvincp, anticorps EG:103B4.1, anticorps Vin, anticorps Vin2EF, anticorps vinc, anticorps LOC100228062, anticorps vcl-A, anticorps vinculin, anticorps vinculin a, anticorps vinculin A, anticorps Vinculin, anticorps vinculin S homeolog, anticorps VCL, anticorps vcla, anticorps vinA, anticorps Vcl, anticorps Vinc, anticorps CpipJ_CPIJ013873, anticorps Bm1_37935, anticorps vcl, anticorps vcl.S
Sujet
Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).
Poids moléculaire
Predicted: 117 kDa Observed: 120 kDa
ID gène
7414
NCBI Accession
NP_003364
Pathways
Cell-Cell Junction Organization , Maintenance of Protein Location , Signaling Events mediated by VEGFR1 and VEGFR2
Vus récemment
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