SYK anticorps (pTyr323)
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- Antigène Voir toutes SYK Anticorps
- SYK (Spleen tyrosine Kinase (SYK))
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Épitope
- pTyr323
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SYK est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Specificité
- This antibody detects endogenous level of syk only when phosphorylated at tyrosine 323.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
- Immunogène
- syk (phospho-Tyr323) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y (p) -E- P) derived from Human syk.
- Top Product
- Discover our top product SYK Anticorps primaire
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- Indications d'application
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store antibody at -20°C for up to one year.
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- Antigène
- SYK (Spleen tyrosine Kinase (SYK))
- Autre désignation
- syk (SYK Produits)
- Synonymes
- anticorps p72-Syk, anticorps Sykb, anticorps p72syk, anticorps spleen associated tyrosine kinase, anticorps spleen tyrosine kinase, anticorps syk, anticorps SYK, anticorps Syk
- Sujet
- Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C γ,dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion
- Poids moléculaire
- 72 kDa
- ID gène
- 6850
- NCBI Accession
- NP_001128524
- UniProt
- P43405
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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