CXCR3 anticorps (C-Term)

N° du produit ABIN5689936

Détail du produit anti-CXCR3 anticorps

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist, this antibody will detect both isoforms.

Purification: CXCR3 antibody is affinity chromatography purified via peptide column.

Immunogène: CXCR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human CXCR3 .

The immunogen is located within the last 50 amino acids of CXCR3.

Isotype: IgG

Information d'application

Indications d'application: CXCR3 antibody can be used for detection of CXCR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CXCR3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: CXCR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CXCR3

Antigène: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Autre désignation: CXCR3 (CXCR3 Produits)

Synonymes: anticorps CD182, anticorps CD183, anticorps CKR-L2, anticorps CMKAR3, anticorps GPR9, anticorps IP10-R, anticorps Mig-R, anticorps MigR, anticorps Cd183, anticorps Cmkar3, anticorps CXCR3, anticorps cxcr3, anticorps Gpr9, anticorps CXC-R3, anticorps CXCR-3, anticorps zgc:92301, anticorps sb:eu378, anticorps C-X-C motif chemokine receptor 3, anticorps chemokine (C-X-C motif) receptor 3, anticorps chemokine (C-X-C motif) receptor 3, tandem duplicate 2, anticorps chemokine (C-X-C motif) receptor 3, tandem duplicate 1, anticorps CXCR3, anticorps Cxcr3, anticorps cxcr3, anticorps cxcr3.2, anticorps cxcr3.1

Sujet: The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) (reviewed in 1). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration (2). Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker of tumor behavior as well as a potential therapeutic target (3).

Poids moléculaire: Predicted: 46 kDa

Observed: 43 kDa

ID gène: 2833

NCBI Accession: NP_001136269

UniProt: P49682