KLF17 anticorps (C-Term)

N° du produit ABIN5690033

Détail du produit anti-KLF17 anticorps

Antigène: KLF17 (Kruppel-Like Factor 17 (KLF17))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: KLF17 antibody is human, mouse and rat reactive. At least two isoforms of KLF17 are known to exist, this antibody will only detect the large isoform. KLF17 antibody is predicted to not cross-react with other KLF proteins.

Purification: KLF17 antibody is affinity chromatography purified via peptide column.

Immunogène: KLF17 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KLF17.

The immunogen is located within the last 50 amino acids of KLF17.

Isotype: IgG

Information d'application

Indications d'application: KLF17 antibody can be used for detection of KLF17 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KLF17 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: KLF17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur KLF17

Antigène: KLF17 (Kruppel-Like Factor 17 (KLF17))

Autre désignation: KLF17 (KLF17 Produits)

Synonymes: anticorps zfp393, anticorps znf393, anticorps neptune, anticorps rp4-675g8.1, anticorps ZNF393, anticorps Zfp393, anticorps 7420700M05Rik, anticorps AA420409, anticorps AU043468, anticorps C85123, anticorps D4Ertd561e, anticorps Gzf, anticorps Kruppel-like factor 17 L homeolog, anticorps Kruppel like factor 17, anticorps Kruppel-like factor 17, anticorps klf17.L, anticorps KLF17, anticorps klf17, anticorps Klf17

Sujet: KLF17, also known as ZNF393, is a member of the Sp/KLF family of transcription factors (1,2). KLF17 binds to the promoter and negatively regulates the transcription of Id-1, a key metastasis regulator in breast cancer (3). Suppression of KLF17 promotes breast cancer cell invasion and epithelial-mesenchymal transition (3). Down-regulated KLF17 expression is also associated tumor invasion and poor prognosis in hepatocellular carcinoma, suggesting that the level of KLF17 expression can serve as a prognostic indicator (4).

Poids moléculaire: Predicted: 28, 39, 43 kDa

Observed: 38 kDa

ID gène: 128209

NCBI Accession: NP_775755

UniProt: Q5JT82