Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) anticorps

N° du produit ABIN5690340

Détail du produit

Antigène: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Épitope: AA 21-33

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Specificité: Recognizes mouse SCD1. Detects a band of ~41  kDa by Western Blot.

Immunogène: Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.

Information d'application

Indications d'application: ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL, suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk, suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. 0.2um-filtered solution in PBS,  pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Stable for at least 6 months after receipt when stored at -20°C.

Détail du antigène

Antigène: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Autre désignation: Stearoyl-CoA Desaturase-1 (SCD1 Produits)

Synonymes: anticorps AA589638, anticorps AI265570, anticorps Scd, anticorps Scd-1, anticorps ab, anticorps stearoyl-Coenzyme A desaturase 1, anticorps Scd1

Sujet: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.

ID gène: 20249

UniProt: P13516

Pathways: Brown Fat Cell Differentiation