GZMB anticorps (AA 21-247)
Aperçu rapide pour GZMB anticorps (AA 21-247) (ABIN5692783)
Antigène
Voir toutes GZMB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-247
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Fonction
- Anti-Granzyme B/Gzmb Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Granzyme B/Gzmb Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived mouse Granzyme B recombinant protein (Position: I21-S247).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- GZMB (Granzyme B (GZMB))
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Autre désignation
- Gzmb
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Sujet
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Background: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Gene Full Name: granzyme B
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Poids moléculaire
- 28 kDa
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ID gène
- 14939
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UniProt
- P04187
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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