EPOR anticorps (AA 32-225)

N° du produit ABIN5693050

L’anticorps anti-EPOR Polyclonal Lapin est utilisé pour la détection de EPOR dans des échantillons de Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour EPOR anticorps (AA 32-225) (ABIN5693050)

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPOR est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EPOR anticorps

Épitope: AA 32-225

Fonction: Anti-EPO Receptor/Epor Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-EPO Receptor/Epor Antibody (ABIN5693050). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Immunogène: E. coli-derived mouse EPO Receptor recombinant protein (Position: D32-E225).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur EPOR

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Autre désignation: Epor

Sujet:

Synonyms: Erythropoietin receptor, EPO-R, Epor

Tissue Specificity: Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells.

Background: The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 55 kDa

ID gène: 13857

UniProt: P14753

Pathways: Signalistation JAK/STAT