EPOR anticorps (pTyr368)

N° du produit ABIN6255901

Cet anticorps anti-EPOR Polyclonal Lapin (ABIN6255901) détecte spécifiquement EPOR dans WB, ELISA, ICC et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour EPOR anticorps (pTyr368) (ABIN6255901)

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPOR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-EPOR anticorps

Épitope: pTyr368

Specificité: Phospho-Epo-R (Tyr368) Antibody detects endogenous levels of Epo-R only when phosphorylated at Tyrosine 368.

Homologie: Pig,Sheep,Dog

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Epo-R around the phosphorylation site of Tyr368.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur EPOR

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Autre désignation: EPOR

Sujet:

Description: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Gene: EPOR

Poids moléculaire: 55kDa

ID gène: 2057

UniProt: P19235

Pathways: Signalistation JAK/STAT