Periaxin anticorps (AA 1-91) (DyLight 488)

N° du produit ABIN7354670

Détail du produit anti-Periaxin anticorps (DyLight 488)

Antigène: Periaxin (PRX)

Épitope: AA 1-91

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Periaxin est conjugé à/à la DyLight 488

Application: Flow Cytometry (FACS)

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG Polyclonal Anti-Human PRX Antibody DyLight® 488 Conjugated, Flow Validated.

Immunogène: E. coli-derived human PRX recombinant protein (Position: M1-K91).

Information d'application

Indications d'application:

Application Details: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: At 2-8°C for one year. Protect from light. Do not freeze.

Détails sur Periaxin

Antigène: Periaxin (PRX)

Autre désignation: PRX (PRX Produits)

Synonymes: anticorps xprx, anticorps MGC89167, anticorps CMT4F, anticorps L-Periaxin, anticorps periaxin, anticorps prx, anticorps PRX, anticorps Prx

Sujet:

Synonyms: Periaxin, PRX, KIAA1620

Tissue Specificity: Detected in spinal cord (PubMed:11133365). Isoform 1 and isoform 2 are found in sciatic nerve and Schwann cells (PubMed:11157804).

Background: Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.