alpha Actinin 4 anticorps
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- Antigène Voir toutes alpha Actinin 4 (ACTN4) Anticorps
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp alpha Actinin 4 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF)
- Immunogène
- actinin, alpha 4
- Isotype
- IgG
- Top Product
- Discover our top product ACTN4 Anticorps primaire
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- Indications d'application
- WB :1:500-1:5000,IHC:1:20-1:200,IP:1:500-1:5000,IF:1:10-1:100
- Commentaires
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00123(ACTN4 antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Autre désignation
- ACTN4 (ACTN4 Produits)
- Synonymes
- anticorps fsgs, anticorps fsgs1, anticorps C77391, anticorps ACTININ-4, anticorps FSGS, anticorps FSGS1, anticorps wu:fb53f05, anticorps zgc:63508, anticorps actinin alpha 4, anticorps actinin, alpha 4, anticorps actinin alpha 4 S homeolog, anticorps actn4, anticorps ACTN4, anticorps Actn4, anticorps actn4.S
- Sujet
- Synonyms:ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, DKFZp686K23158, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4 Background:F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).
- Poids moléculaire
- 105kDa
- ID gène
- 81
- UniProt
- O43707
- Pathways
- Proton Transport
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