AFF4 anticorps

N° du produit ABIN5696888

Détail du produit anti-AFF4 anticorps

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogène: AF4/FMR2 family, member 4

Isotype: IgG

Information d'application

Indications d'application: WB :1:200-1:2000,IP:1:200-1:1000

Commentaires:

L02 cells were subjected to SDS PAGE followed by western blot with FNab00197(AFF4 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur AFF4

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Autre désignation: AFF4 (AFF4 Produits)

Synonymes: anticorps AFF4, anticorps RA_m002_jsmFBA6Br, anticorps AF5Q31, anticorps MCEF, anticorps Alf4, anticorps Laf4l, anticorps AF4/FMR2 family member 4 L homeolog, anticorps AF4/FMR2 family member 4, anticorps AF4/FMR2 family, member 4, anticorps aff4.L, anticorps AFF4, anticorps aff4, anticorps Aff4

Sujet: Synonyms:AF4/FMR2 family member 4, AF4/FMR2 family, member 4, AF5Q31, AFF4, MCEF, Protein AF 5q31 Background:Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Poids moléculaire: 127kDa,observed 150kDa

ID gène: 27125

UniProt: Q9UHB7