RBM25 anticorps

N° du produit ABIN5698254

Détail du produit anti-RBM25 anticorps

Antigène: RBM25 (RNA Binding Motif Protein 25 (RBM25))

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM25 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: RNA binding motif protein 25

Isotype: IgG

Information d'application

Indications d'application: WB : 1:200-1:2000 IP : 1:200-1:2000 IHC : 1:20-1:200

Commentaires:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07171( RBM25 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur RBM25

Antigène: RBM25 (RNA Binding Motif Protein 25 (RBM25))

Autre désignation: RBM25 (RBM25 Produits)

Synonymes: anticorps fi03e10, anticorps zgc:56208, anticorps wu:fi03e10, anticorps si:ch211-105d18.5, anticorps rnpc7, anticorps s164, anticorps NET52, anticorps RED120, anticorps RNPC7, anticorps S164, anticorps Snu71, anticorps fSAP94, anticorps 2600011C06Rik, anticorps 2610015J01Rik, anticorps A130095G20Rik, anticorps AI159652, anticorps AL023075, anticorps AU043498, anticorps RNA binding motif protein 25b, anticorps RNA binding motif protein 25, anticorps RNA binding motif protein 25 S homeolog, anticorps putative rna binding motif protein 25, anticorps rbm25b, anticorps Rbm25, anticorps rbm25.S, anticorps rbm25, anticorps RBM25, anticorps Smp_078610

Sujet: Synonyms:fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164 Background:RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site(5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.

Poids moléculaire: 110-120 kDa

ID gène: 58517

UniProt: P49756