SMURF1 anticorps

N° du produit ABIN5698391

Détail du produit anti-SMURF1 anticorps

Antigène: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMURF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: SMAD specific E3 ubiquitin protein ligase 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08046(SMURF1 antibody) at dilution of 1:800

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur SMURF1

Antigène: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Autre désignation: SMURF1 (SMURF1 Produits)

Synonymes: anticorps 4930431E10Rik, anticorps mKIAA1625, anticorps RGD1309707, anticorps SMAD specific E3 ubiquitin protein ligase 1, anticorps E3 ubiquitin-protein ligase SMURF1, anticorps SMAD specific E3 ubiquitin protein ligase 1 L homeolog, anticorps SMURF1, anticorps LOC100540915, anticorps smurf1, anticorps Smurf1, anticorps smurf1.L

Sujet: Synonyms:KIAA1625 Background:E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes(PubMed:23999003).

ID gène: 57154

UniProt: Q9HCE7

Pathways: Regulation of Cell Size