MED12 anticorps

N° du produit ABIN5699865

Détail du produit anti-MED12 anticorps

Antigène: MED12 (Mediator Complex Subunit 12 (MED12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED12 est non-conjugé

Application: ELISA, Western Blotting (WB)

Immunogène: mediator complex subunit 12

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur MED12

Antigène: MED12 (Mediator Complex Subunit 12 (MED12))

Autre désignation: MED12 (MED12 Produits)

Synonymes: anticorps ARC240, anticorps CAGH45, anticorps FGS1, anticorps HOPA, anticorps MED12S, anticorps OHDOX, anticorps OKS, anticorps OPA1, anticorps TNRC11, anticorps TRAP230, anticorps 230kDa, anticorps Mopa, anticorps OPA-1, anticorps Tnrc11, anticorps Trap230, anticorps mediator complex subunit 12, anticorps MED12, anticorps Med12, anticorps med12

Sujet: Synonyms:ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230 Background:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

Poids moléculaire: 230 kDa

ID gène: 9968

UniProt: Q93074

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation