CEP63 anticorps
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- Antigène Voir toutes CEP63 Anticorps
- CEP63 (Centrosomal Protein 63kDa (CEP63))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CEP63 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogène
- centrosomal protein 63kDa
- Isotype
- IgG
- Top Product
- Discover our top product CEP63 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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human placenta tissue were subjected to SDS PAGE followed by western blot with FNab01606(CEP63 antibody) at dilution of 1:800
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- CEP63 (Centrosomal Protein 63kDa (CEP63))
- Autre désignation
- CEP63 (CEP63 Produits)
- Synonymes
- anticorps 4921501M07, anticorps AL450317.13gm1, anticorps AW107703, anticorps CD20R, anticorps D9Mgc41, anticorps D9Mgc48e, anticorps ET2, anticorps zgc:63548, anticorps Cep63-A, anticorps Cep63-B, anticorps Xcep63, anticorps centrosomal protein 63, anticorps centrosomal protein 63kDa, anticorps centrosomal protein 63kDa L homeolog, anticorps CEP63, anticorps SYO3AOP1_1060, anticorps Cep63, anticorps cep63, anticorps cep63.L
- Sujet
- Synonyms: Background:Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152, however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398).
- Poids moléculaire
- 57-75 kDa
- ID gène
- 80254
- UniProt
- Q96MT8
- Pathways
- M Phase
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