F-Box Protein 3 anticorps

N° du produit ABIN5699902

Détail du produit anti-F-Box Protein 3 anticorps

Antigène: F-Box Protein 3 (FBXO3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F-Box Protein 3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Immunogène: F-box protein 3

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur F-Box Protein 3

Antigène: F-Box Protein 3 (FBXO3)

Autre désignation: FBXO3 (FBXO3 Produits)

Synonymes: anticorps FBA, anticorps FBX3, anticorps 1200002G09Rik, anticorps 1700026K02Rik, anticorps AI046358, anticorps Fba, anticorps zgc:112485, anticorps DKFZp459H187, anticorps F-box protein 3, anticorps F-box protein 3 S homeolog, anticorps FBXO3, anticorps Fbxo3, anticorps fbxo3.S, anticorps fbxo3

Sujet: Synonyms:FBX3 Background:Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

Poids moléculaire: 48-50 kDa

ID gène: 26273

UniProt: Q9UK99