PHACTR4 anticorps

N° du produit ABIN5699932

Détail du produit anti-PHACTR4 anticorps

Antigène: PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHACTR4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Immunogène: phosphatase and actin regulator 4

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur PHACTR4

Antigène: PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))

Autre désignation: PHACTR4 (PHACTR4 Produits)

Synonymes: anticorps 3110001B12Rik, anticorps AI527228, anticorps AW495572, anticorps C330013F19Rik, anticorps N28169, anticorps mKIAA4120, anticorps phactr4, anticorps zgc:63484, anticorps zgc:123224, anticorps phosphatase and actin regulator 4, anticorps phosphatase and actin regulator 4b, anticorps phosphatase and actin regulator 4 L homeolog, anticorps phosphatase and actin regulator 4 S homeolog, anticorps phosphatase and actin regulator 4a, anticorps Phactr4, anticorps phactr4b, anticorps PHACTR4, anticorps phactr4.L, anticorps phactr4.S, anticorps Tsp_08786, anticorps phactr4, anticorps phactr4a

Sujet: Synonyms: Background:Regulator of protein phosphatase 1(PP1) required for neural tube and optic fissure closure, and enteric neural crest cell(ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells(ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin(COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway(By similarity).

ID gène: 65979

UniProt: Q8IZ21

Pathways: Tube Formation