HMGB1 anticorps

N° du produit ABIN5700962

L’anticorps anti-HMGB1 Polyclonal Lapin est utilisé pour la détection de HMGB1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IP.

Aperçu rapide pour HMGB1 anticorps (ABIN5700962)

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-HMGB1 anticorps

Fonction: HMGB1 antibody

Immunogène: high-mobility group box 1

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5000,IP:1:200-1:2000,IHC:1:50-1:200

Commentaires:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03924(HMGB1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur HMGB1

Antigène: HMGB1 (High Mobility Group Box 1 (HMGB1))

Autre désignation: HMGB1

Sujet:

Synonyms: High mobility group protein B1|High mobility group protein 1 (HMG-1)|HMGB1|HMG1

Background: This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Poids moléculaire: 30 kDa

ID gène: 3146

UniProt: P09429

Pathways: Signalisation p53, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome