USP44 anticorps
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- Antigène Voir toutes USP44 Anticorps
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp USP44 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Immunogène
- ubiquitin specific peptidase 44
- Isotype
- IgG
- Top Product
- Discover our top product USP44 Anticorps primaire
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- Indications d'application
- WB : 1:500-1:5000
- Commentaires
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human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09334(USP44 antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
- Autre désignation
- USP44 (USP44 Produits)
- Synonymes
- anticorps usp44, anticorps USP49, anticorps E430004F17Rik, anticorps zgc:55661, anticorps ubiquitin specific peptidase 44, anticorps ubiquitin specific peptidase 44 L homeolog, anticorps ubiquitin specific peptidase 44 S homeolog, anticorps USP44, anticorps usp44.L, anticorps usp44.S, anticorps usp44, anticorps Usp44
- Sujet
- Synonyms:Deubiquitinating enzyme 44, DKFZp434D0127, FLJ14528, Ubiquitin thiolesterase 44, USP44 Background:Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination.
- Poids moléculaire
- 145kDa
- ID gène
- 84101
- UniProt
- Q9H0E7
- Pathways
- M Phase
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