ATP8A1 anticorps

N° du produit ABIN5702410

Détail du produit anti-ATP8A1 anticorps

Antigène: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP8A1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Immunogène: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur ATP8A1

Antigène: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Autre désignation: ATP8A1 (ATP8A1 Produits)

Synonymes: anticorps ATPASEII, anticorps ATPIA, anticorps ATPP2, anticorps AI481521, anticorps AI853962, anticorps APLT, anticorps AW743152, anticorps AW822227, anticorps Atp3a2, anticorps B230107D19Rik, anticorps ClassI, anticorps mKIAA4233, anticorps ATPase phospholipid transporting 8A1, anticorps ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1, anticorps Atp8a1, anticorps ATP8A1

Sujet: Synonyms:ATP8A1, ATPase II, ATPASEII, ATPIA, ATPP2, Chromaffin granule ATPase II Background:Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine(PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine(PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

Poids moléculaire: 120 kDa

ID gène: 10396

UniProt: Q9Y2Q0