STT3A anticorps

N° du produit ABIN5703191

Détail du produit anti-STT3A anticorps

Antigène: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STT3A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Immunogène: STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08355( STT3A Antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur STT3A

Antigène: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Autre désignation: STT3A (STT3A Produits)

Synonymes: anticorps cb437, anticorps wu:fb38c11, anticorps AA408947, anticorps BB081708, anticorps Itm1, anticorps ITM1, anticorps STT3-A, anticorps TMC, anticorps STT3A, subunit of the oligosaccharyltransferase complex (catalytic), anticorps STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae), anticorps STT3A, catalytic subunit of the oligosaccharyltransferase complex, anticorps stt3a, anticorps Stt3a, anticorps STT3A

Sujet: Synonyms:B5, Integral membrane protein 1, ITM1, STT3 A, STT3A, TMC, Transmembrane protein TMC Background:Catalytic subunit of the N-oligosaccharyl transferase(OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum(ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

ID gène: 3703

UniProt: P46977