IFIT2 anticorps
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- Antigène Voir toutes IFIT2 Anticorps
- IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IFIT2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogène
- interferon-induced protein with tetratricopeptide repeats 2
- Isotype
- IgG
- Top Product
- Discover our top product IFIT2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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A431 cells were subjected to SDS PAGE followed by western blot with FNab04137( IFIT2 Antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
- Autre désignation
- IFIT2 (IFIT2 Produits)
- Synonymes
- anticorps G10P2, anticorps GARG-39, anticorps IFI-54, anticorps IFI-54K, anticorps IFI54, anticorps IFIT-2, anticorps ISG-54 K, anticorps ISG-54K, anticorps ISG54, anticorps P54, anticorps cig42, anticorps wu:fb58d07, anticorps DKFZp468G198, anticorps AV302338, anticorps Ifi54, anticorps interferon induced protein with tetratricopeptide repeats 2, anticorps interferon-induced protein with tetratricopeptide repeats 2, anticorps interferon-induced protein with tetratricopeptide repeats 15, anticorps IFIT2, anticorps Ifit2, anticorps ifit15
- Sujet
- Synonyms:cig42, G10P2, GARG 39, IFI 54, IFI 54K, IFI54, IFIT 2, IFIT2, ISG 54 K, ISG 54K, ISG54 Background:IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
- Poids moléculaire
- 50-55 kDa
- ID gène
- 3433
- UniProt
- P09913
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