SMARCD1 anticorps
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- Antigène Voir toutes SMARCD1 Anticorps
- SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SMARCD1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogène
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
- Isotype
- IgG
- Top Product
- Discover our top product SMARCD1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08010(SMARCD1 antibody) at dilution of 1:600
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))
- Autre désignation
- SMARCD1 (SMARCD1 Produits)
- Synonymes
- anticorps rsc6p, anticorps baf60a, anticorps cracd1, anticorps MGC69403, anticorps BAF60A, anticorps CRACD1, anticorps Rsc6p, anticorps wu:fa10h07, anticorps wu:fb82d01, anticorps wu:fi45f10, anticorps AA407987, anticorps Baf60a, anticorps D15Kz1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 L homeolog, anticorps SMARCD1, anticorps smarcd1, anticorps smarcd1.L, anticorps Smarcd1
- Sujet
- Synonyms:BAF60A Background:Involved in chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex(npBAF complex) and the neuron-specific chromatin remodeling complex(nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes(nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth(By similarity). Has a strong influence on vitamin D-mediated transcriptional activity from an enhancer vitamin D receptor element(VDRE). May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor(VDR) heterodimer. Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation.
- ID gène
- 6602
- UniProt
- Q96GM5
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