CCDC22 anticorps

N° du produit ABIN5705501

Détail du produit anti-CCDC22 anticorps

Antigène: CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC22 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: coiled-coil domain containing 22

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CCDC22

Antigène: CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))

Autre désignation: CCDC22 (CCDC22 Produits)

Synonymes: anticorps CXorf37, anticorps AI481216, anticorps DXImx40e, anticorps Ppp1r3f, anticorps Sfc22, anticorps RGD1560910, anticorps zgc:114058, anticorps coiled-coil domain containing 22, anticorps CCDC22, anticorps Ccdc22, anticorps ccdc22

Sujet: Synonyms:CXorf37 Background:Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation, the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via assocation with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10(PubMed:23563313). Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery, the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes(PubMed:25355947).

Poids moléculaire: 71 kDa

ID gène: 28952

UniProt: O60826