TELO2 anticorps

N° du produit ABIN5705560

Détail du produit anti-TELO2 anticorps

Antigène: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TELO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Immunogène: TEL2, telomere maintenance 2, homolog (S. cerevisiae)

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

A431 cells were subjected to SDS PAGE followed by western blot with FNab08592(TELO2 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TELO2

Antigène: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Autre désignation: TELO2 (TELO2 Produits)

Synonymes: anticorps RGD1305553, anticorps 1200003M09Rik, anticorps AI415602, anticorps Tel2, anticorps mKIAA0683, anticorps CLK2, anticorps TEL2, anticorps telomere maintenance 2, anticorps Telo2, anticorps TELO2

Sujet: Synonyms:KIAA0683 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.

ID gène: 9894

UniProt: Q9Y4R8