TRIAP1 anticorps

N° du produit ABIN5705911

Détail du produit anti-TRIAP1 anticorps

Antigène: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIAP1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Immunogène: TP53 regulated inhibitor of apoptosis 1

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5000

Commentaires:

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 15351-1-AP( TRIAP1 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TRIAP1

Antigène: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Autre désignation: TRIAP1 (TRIAP1 Produits)

Synonymes: anticorps MDM35, anticorps P53CSV, anticorps WF-1, anticorps 1810015M01Rik, anticorps AU020874, anticorps AU043831, anticorps P53csv, anticorps Wf-1, anticorps p53csv-A, anticorps triap1, anticorps triap1a, anticorps p53csv-B, anticorps triap1-a, anticorps triap1-b, anticorps triap1b, anticorps zgc:112025, anticorps TP53 regulated inhibitor of apoptosis 1, anticorps TP53 regulated inhibitor of apoptosis 1 S homeolog, anticorps TP53 regulated inhibitor of apoptosis 1 L homeolog, anticorps TRIAP1, anticorps Triap1, anticorps triap1.S, anticorps triap1.L, anticorps triap1

Sujet: Synonyms:15E1.1, HSPC132, P53CSV, Protein 15E1.1, TRIAP1, WF 1 Background:Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).

Poids moléculaire: 32kDa

ID gène: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling