CD14 anticorps (AA 16-260)

N° du produit ABIN5708067

L’anticorps anti-CD14 Polyclonal Lapin est utilisé pour la détection de CD14 dans des échantillons de Souris et Rat. Il a été validé pour FACS, WB et IHC (p).

Aperçu rapide pour CD14 anticorps (AA 16-260) (ABIN5708067)

Antigène: CD14

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD14 anticorps

Épitope: AA 16-260

Fonction: Cd14 Antibody

Purification: Antigen affinity

Immunogène: A recombinant mouse protein corresponding to amino acids S16-A260 was used as the immunogen for the Cd14 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cd14 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Cd14 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD14

Antigène: CD14

Autre désignation: Cd14

Sujet: CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55 kDa glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. This gene is located at bands 5q23-q31. The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.

UniProt: P10810

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades