Neurexin 1 anticorps

N° du produit ABIN5708329

Détail du produit anti-Neurexin 1 anticorps

Antigène: Neurexin 1 (NRXN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurexin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids D141-E294 was used as the immunogen for the Neurexin 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Neurexin 1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Neurexin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Neurexin 1

Antigène: Neurexin 1 (NRXN1)

Autre désignation: Neurexin 1 (NRXN1 Produits)

Synonymes: anticorps Hs.22998, anticorps PTHSL2, anticorps SCZD17, anticorps CG7050, anticorps CT21808, anticorps Dmel\\CG7050, anticorps Nrx, anticorps Nrx1, anticorps dnrx, anticorps dnrx-1, anticorps nrx, anticorps Nrxn1b, anticorps NRXN1, anticorps Nrx-1, anticorps GB13455, anticorps GB18754, anticorps 1700062G21Rik, anticorps 9330127H16Rik, anticorps A230068P09Rik, anticorps mKIAA0578, anticorps neurexin 1, anticorps Neurexin 1, anticorps neurexin I, anticorps neurexin 1b, anticorps neurexin 1a, anticorps NRXN1, anticorps Nrx-1, anticorps Nrxn1, anticorps nrxn1, anticorps nrxn1b, anticorps nrxn1a

Sujet: Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development