GALE anticorps
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- Antigène Voir toutes GALE Anticorps
- GALE (UDP-Galactose-4-Epimerase (GALE))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GALE est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity purified
- Immunogène
- A recombinant human partial protein corresponding to amino acids M1-N340 was used as the immunogen for the GALE antibody.
- Isotype
- IgG
- Top Product
- Discover our top product GALE Anticorps primaire
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- Indications d'application
- Optimal dilution of the GALE antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the GALE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- GALE (UDP-Galactose-4-Epimerase (GALE))
- Autre désignation
- GALE / UDP-glucose 4-epimerase (GALE Produits)
- Synonymes
- anticorps GALE, anticorps im:7147391, anticorps wu:fb05f01, anticorps zgc:136578, anticorps F15H21.11, anticorps F15H21_11, anticorps REB1, anticorps ROOT EPIDERMAL BULGER1, anticorps ROOT HAIR DEFECTIVE 1, anticorps UDP-GLUCOSE 4-EPIMERASE, anticorps UGE4, anticorps ECK0748, anticorps galD, anticorps JW0742, anticorps SMU.888, anticorps BA5505, anticorps BA5700, anticorps VFA0352, anticorps galE, anticorps 2310002A12Rik, anticorps AI323962, anticorps 1n569, anticorps xgale, anticorps SDR1E1, anticorps UDP-galactose-4-epimerase, anticorps NAD(P)-binding Rossmann-fold superfamily protein, anticorps UDP-galactose 4-epimerase GalE, anticorps UDP-glucose 4-epimerase, anticorps UDP-glucose 4-epimerase GalE, anticorps UDP-glucose/UDP-N-acetylglucosamine 4-epimerase, anticorps galactose-4-epimerase, UDP, anticorps UDP-galactose-4-epimerase L homeolog, anticorps GALE, anticorps gale, anticorps RHD1, anticorps ECs0787, anticorps galE, anticorps galE1, anticorps galE2, anticorps STY0809, anticorps galE-2, anticorps SG0897, anticorps galD, anticorps Ent638_1250, anticorps Gale, anticorps gale.L
- Sujet
- The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
- UniProt
- Q14376
- Pathways
- Response to Water Deprivation, Cellular Glucan Metabolic Process
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