EGFR anticorps (Extracellular Domain) (PE)
Aperçu rapide pour EGFR anticorps (Extracellular Domain) (PE) (ABIN576424)
Antigène
Voir toutes EGFR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Specificité
- Recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis. Binds to epitope B from EGFR and has an affinity of 6.7 x 10-9 M.
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Purification
- Protein G purified
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Immunogène
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Extracellular domain of human EGF-receptor from head and neck carcinoma.
Type of Immunogen: Recombinant protein -
Isotype
- IgG2a
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anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 7A6F12 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibodyEGFR Reactivité: Humain WB, IHC Hôte: Souris Monoclonal C4 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1163-1191), (C-Term) antibodyEGFR Reactivité: Humain WB, IHC (p) Hôte: Souris Monoclonal 688CT33-1-3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR Reactivité: Humain, Souris, Rat, Porc, Singe, Boeuf (Vache), Poulet, Chien, Cheval, Lapin, Cobaye, Avian, Cat, Âne, Chévre, Hamster, Mouton WB Hôte: Chèvre Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibodyEGFR Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 5E10D3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibodyEGFR Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibodyEGFR Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibodyEGFR Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR Reactivité: Humain, Rat WB, ELISA, IHC, IP Hôte: Lapin Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibodyEGFR Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Approved: Flo (1:1)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 1 mL distilled water.
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Concentration
- Lot specific
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Buffer
- Lyophilized powder from PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light.
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Stock
- 4 °C
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Stockage commentaire
- Store at 4°C. Do not freeze. Protect from light.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Autre désignation
- EGFR
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Sujet
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Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1 -
ID gène
- 1956
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Antigène
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