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CD3 epsilon anticorps (AA 23-126)

Cet anticorps anti-CD3 epsilon est un anticorps Souris Monoclonal détectant CD3 epsilon dans FACS, WB, IF, ELISA et ICC. Adapté pour Humain.
N° du produit ABIN5776073

Aperçu rapide pour CD3 epsilon anticorps (AA 23-126) (ABIN5776073)

Antigène

Voir toutes CD3 epsilon (CD3E) Anticorps
CD3 epsilon (CD3E)

Reactivité

  • 351
  • 207
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Humain

Hôte

  • 209
  • 175
  • 47
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  • 7
  • 2
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Souris

Clonalité

  • 394
  • 115
  • 7
Monoclonal

Conjugué

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Cet anticorp CD3 epsilon est non-conjugé

Application

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Clone

AT3H3
  • Épitope

    • 61
    • 41
    • 26
    • 16
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    AA 23-126

    Fonction

    Human CD3 epsilon/CD3E antibody

    Purification

    Purified

    Immunogène

    Recombinant human CD3E (23-126aa) purified from E. coli

    Isotype

    IgG1 kappa
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • Antigène

    CD3 epsilon (CD3E)

    Autre désignation

    CD3 epsilon/CD3E

    Sujet

    The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multi subunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

    NCBI Accession

    NP_000724

    Pathways

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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