IL4 Receptor anticorps (Tyr497)

N° du produit ABIN5956943

Cet anticorps Lapin Polyclonal détecte spécifiquement IL4 Receptor dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour IL4 Receptor anticorps (Tyr497) (ABIN5956943)

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL4 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-IL4 Receptor anticorps

Épitope: Tyr497

Specificité: CD124,IL 4R alpha,IL-4 receptor subunit alpha,IL-4-binding protein,IL-4R subunit alpha,IL-4R-alpha,IL-4RA,IL4-BP,Il4r,IL4R nirs variant 1,IL4RA,IL4RA,Interleukin 4 receptor alpha chain,Interleukin 4 receptor,sIL4Ralpha/prot,Soluble IL-4 receptor subunit alpha,Soluble IL-4R-alpha,Soluble interleukin-4 receptor subunit alpha

Purification: Affinity purification

Immunogène: Synthesized peptide derived from human IL-4Ralpha around the non-phosphorylation site of Tyr497.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IL4 Receptor

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Autre désignation: IL-4Ralpha

Sujet: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammmation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.

Poids moléculaire: 90kDa

ID gène: 3566

UniProt: P24394

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process