CMA1 anticorps

N° du produit ABIN5958200

Détail du produit anti-CMA1 anticorps

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMA1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Alpha-chymase,Chymase 1,Chymase 1 mast cell,chymase 1 preproprotein transcript E,chymase 1 preproprotein transcript I,Chymase,Chymase,heart,Chymase,mast cell,CMA1,CMA1,CYH,CYM,EC 3.4.21.39,Mast cell chymase 1,Mast cell protease 3,Mast cell protease 5,Mast cell protease I,Mast cell protease III,Mcp-5,MCP3P,Mcpt5,MCT1,MGC119890,MGC119891,MMCP-5

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human Chymase.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CMA1

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Autre désignation: Chymase (CMA1 Produits)

Synonymes: anticorps CYH, anticorps MCT1, anticorps chymase, anticorps MMCP-5, anticorps Mcp-5, anticorps Mcp5, anticorps Mcpt5, anticorps MCP3P, anticorps CMA1, anticorps Chymase, anticorps chymase 1, anticorps chymase 1, mast cell, anticorps chymase-like, anticorps CMA1, anticorps Cma1, anticorps LOC100008644

Sujet: This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.CMA1 (Chymase 1) is a Protein Coding gene. Diseases associated with CMA1 include Urticaria Pigmentosa and Urticaria. Among its related pathways are Degradation of the extracellular matrix and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. GO annotations related to this gene include serine-type endopeptidase activity and peptide binding. An important paralog of this gene is GZMB.

Poids moléculaire: 27kDa

ID gène: 1215

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis